IL6 and cancer: EGCG alters genes related to epigenetic modificationand cell proliferation,including chromatin-modifying genes (histone acetyltransferases andhistone deacetylases) that control NF-kappa B subunit RELA and itsdownstream genes, like IL6, involved in cell proliferation and migration.−,  The epigenetic effects of EGCG on cancer chemoprevention have alsobeen investigated through the assessment of global DNA methylationand expression of genes related to DNA methylation, such as DNA methyltransferaseenzymes (DNMTs), and genes related to chromatin modification.,