CXCL8 and hemolytic-uremic syndrome: Although no significant differences in clinical characteristics were observed between groups, those who developed TTP/HUS had significantly higher H. pylori positivity rates (p < 0.05), as well as elevated levels of interleukin (IL)-12 and IL-8 during leukocyte recovery and at the onset of TTP/HUS (both p < 0.05)[11].