Other individual or environmental factors not captured in our study, such as actual individual adherence to chemoprophylaxis (despite sensitization efforts), genetic variations beyond blood groups (e.g., Glucose-6-phosphate dehydrogenase (G6PD) deficiency or sickle cell traits, which also offer protection against severe malaria [14]), or the precise intensity of local transmission in specific deployment micro-environments, might have a predominant impact on malaria incidence, recurrence, or severity. The gene discussed is G6PD; the disease is G6PD deficiency.