PGF and hypertensive disorder: The pentamarker panel, which includes biomarkers such as pregnancy-associated plasma protein A (PAPP-A), placental growth factor (PlGF), alpha-fetoprotein, beta-human chorionic gonadotropin, and inhibin A, along with bilateral uterine artery pulsatility index (PI), has shown promise as a predictive tool for hypertensive disorders during pregnancy.