In the analysis of pentamarker components, significant differences were observed between the preeclampsia and normotensive groups, with preeclampsia patients showing lower PlGF levels (108.2±34.5 pg/mL vs. 186.4±42.7 pg/mL) and higher uterine artery PI (2.08±0.33 vs. 1.47±0.28), both with p-values <0.001. This evidence concerns the gene PGF and preeclampsia.