SREBF1 and head and neck squamous cell carcinoma: SREBP1 acts as a key transcription factor in fatty acid synthesis and promotes immune cell infiltration in HNSCC by up-regulating steroidogenic acute regulatory protein-related lipid transport protein 4 (STARD4).92, 93, 94, 95 Furthermore, the natural compound resveratrol regulates SREBP1 expression, inhibits lipid metabolism, and induces autophagy in OSCC.