,29 GLUT1 plays a pivotal role in the malignant progression of oral squamous cell carcinoma (OSCC), and its overexpression is associated with augmented proliferation and invasion of OSCC cells and poor prognosis.30, 31, 32 GLUT4 is aberrantly overexpressed in HNSCC, promotes the proliferation and invasion of cancer cells through the tripartite motif-containing 24 (TRIM24)-DDX58 axis, and is associated with poor prognosis.33 The gene discussed is SLC2A1; the disease is cancer.