FUT1 targets the fucosylation of CD147, intercellular adhesion molecule 1 (ICAM-1), EGFR, and EPH receptor A2 (EPHA2), consequently converging on the down-regulation of AKT/mTOR/eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) signaling to enhance cancer stemness.132. The gene discussed is ICAM1; the disease is cancer.