The results demonstrated that, compared with the control group, RAB26 knockdown decreased the positive rate of Ki-67, RAB26, N-cadherin, vimentin, TWIST1, Bmi1, NANOG, and SOX2 and increased the positive rate of E-cadherin (Fig. 5F, G), suggesting that RAB26 expression was related to tumor growth, EMT, and stemness. Here, SOX2 is linked to neoplasm.