Similarly, mice implanted with eIF4E and eIF4A1 knockdown (KD) ID8 Trp53−/−;Brca2−/− cells (Figure S1Q,R, Supporting Information) had a decreased volume of ascites and tumor burden as compared to the control group (Figure 1–M and Figure S1S–U, Supporting Information). This evidence concerns the gene EIF4A1 and neoplasm.