GPT and Hepatic fibrosis: On CCl4, the high-fat diet plus alcohol rat model, the tectorigenin treatment greatly decreased the histological average scores of hepatic fibrosis from 2.9 to 1.2 (max = 4); inhibited alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum fibrosis markers; and improved antioxidant activity, and the ratio of albumin to globulin.