To investigate whether the confirmed target gene RBMS3 was involved in miRNA‐21a‐5p‐mediated regulation of angiogenesis after TIA, a constructed AAV specifically interfering with RBMS3 expression (AAV‐shRBMS3) or AAV‐control was injected into the ipsilateral striatum and cortex 21 days before TIA modeling. Here, RBMS3 is linked to transient ischemic attack.