Mutaz Amin's team has successively revealed the role of nuclear receptor subfamily 3 Group C member (NR3C1) Gene, corticotropin‐releasing hormone receptor 2 (CRHR2) Gene, and Melanocortin Receptor Genes in the comorbidity of familial diabetes and depression [8, 9, 38]. The gene discussed is CRHR2; the disease is depressive symptom measurement.