This was a larger magnitude of effect than that seen in other diseases where IL-6 signalling is implicated: rheumatoid arthritis (OR 0.54, 95% CI 0.40–0.73); critical COVID-19 (OR 0.66, 95% CI 0.53–0.81); myocardial infarction (OR 0.77, 95% CI 0.66–0.91). The gene discussed is IL6; the disease is rheumatoid arthritis.