TPR and amyotrophic lateral sclerosis: The results (Fig. 2) demonstrate that TPR NUP is highly expressed in spinal cord motor neurons in control conditions, without evident changes in ALS patients, neither at grey matter (Fig. 2A and B) nor at the white matter of anterior horn of spinal cord, where nuclei (i.e. glial cells) showed also high staining of TPR (Fig. 2C and D).