Interestingly, a similar pattern was seen for insulin secretion, fasting glucose, and fasting insulin, whereas MODY cases had similar body mass index (BMI), lipodystrophy, and T1D GRS to controls (P > .05).36 It was also possible to estimate that overall common genetic variation contributes around 24% of phenotypic variance for MODY. This evidence concerns the gene INS and MODY.