Apoptosis profiling was conducted using Annexin V and propidium iodide (PI) staining to evaluate the extent of apoptosis among different experimental groups, including the control (CT), psoriasis-induced (Ps), and treated groups: bone marrow-derived mesenchymal stem cells (Ps + SCs), EGCG nanoparticles (Ps + EGN), mesenchymal stem cell-derived exosomes (Ps + Exo), and the combination of both treatments (Ps + EGN-Exo). This evidence concerns the gene ANXA5 and psoriasis.