SEMA4D and neoplasm: From our ranked list of adhesion proteins, we found expression of SEMA4C, SEMA4D, and SEMA4A in treatment-naïve breast cancer32 (Supplementary Fig. S6k); however, only SEMA4C was detected in breast cancer cells (human/mouse cell lines and/or PDX tumor cells) via immunoblot analyses and mass spectrometry (Fig. 4a, b, and Supplementary Data 1).