Using human tumor cell-THP1 clusters at an optimized 1:4 ratio and anti-PLXNB2 antibody for co-immunoprecipitation, we also detected the enrichment of SEMA4A and CDC42 in the PLXNB2 protein complex, compared to monocytes only (Fig. 5f, g). The gene discussed is SEMA4A; the disease is neoplasm.