In addition, Escherichia-Shigella and unclassified_f_Enterobacteriaceae were positively correlated with tumor size and the proliferation-related antigen Ki67, suggesting that Escherichia-Shigella and unclassified_f_Enterobacteriaceae might play important roles in NSCLC progression. This evidence concerns the gene MKI67 and non-small cell lung carcinoma.