Dogs without stays abroad showed significantly higher HES (n = 113, median: 6), CRP (n = 60, median: 116.2 mg/l), and levels of parasitemia (n = 92, median: 2916 × 103 parasites/ml), but lower serum antibody levels (n = 59, median: 1.5 TE) compared with imported dogs (HES: n = 55, median: 2; CRP: n = 23, median: 40.0 mg/l; levels of parasitemia: n = 29, median: 23 × 103 parasites/ml; antibodies: n = 37, median: 60.6 TE) (P < 0.001 each). Here, CRP is linked to parasitic infectious disease.