In a series of 22 patients with GPIHBP1-AAS, 14 had diagnosed or suspected overlapping autoimmune disease (6 with systemic lupus erythematosus; 4 with Hashimoto disease; and several with an assortment of other conditions including rheumatoid arthritis, Sjögren disease, and antiphospholipid syndrome).2 Here, GPIHBP1 is linked to antiphospholipid syndrome.