The anti-SSA/Ro antibody, a common autoimmune marker, can be detected in various diseases, including systemic lupus erythematosus (SLE), Sjögren’s syndrome (SS), systemic sclerosis (SSc), rheumatoid arthritis (RA), autoimmune liver disease, and myositis [21,22]. The gene discussed is CALR; the disease is systemic sclerosis.