SYS1 and infection: For the early infection screen, along with heparan sulfate and COG complex-related genes, additional host factors impacting RSV infection were identified, including those related to the Golgi (ARFRP1, SYS1, and UNC50), V-ATPase (ATP6V1B2), vesicle trafficking (TRAPPC1), and membrane trafficking (RAB4A) (Fig. 3C).