PLA2R1 and nephrotic syndrome: Patients with baseline eGFR ≥ 30 ml/min per 1.73 m2 and no previous IS were less likely to develop ESKD and worsening kidney function (Supplementary Figures S6A and B, and S7A and B) No significant differences in renal survival were observed concerning PLA2R status, baseline PLA2R-Ab levels (≥116 U/ml vs. < 116 U/ml), nephrotic syndrome at baseline, the presence of FSGS lesion, or IFTA > 25% (log-rank P > 0.05).