Compared to participants not developing AF, those developing AF had a higher age (53.3 ± 12.0 vs 65.4 ± 8.4 years, P < 0.001), were less often females (52.1% vs 27.9%, P < 0.001), and had higher levels of IGFBP7 (84.3 [74.8, 95.4] vs 98.1 [97.3, 111.0] μg/L, P < 0.001). Here, IGFBP7 is linked to atrial fibrillation.