Additionally, determining IP-10 along with IFN-γ in plasma samples from blood stimulated with PPDb and defined TB antigens (ESAT-6, CFP-10, Rv3615c and TB7.7), was shown to identify additional confirmed TB positive animals in comparison to skin test and IGRA alone in cattle [14], and African buffaloes [13] respectively. This evidence concerns the gene CXCL10 and tuberculosis.