Consistently, the analysis of a GSE114922 public dataset [39] revealed that E2F targets, including PLK1, were expressed at a higher level in BM CD34+ cells from MDS–non-IB and MDS with ringed sideroblasts (MDS–RS) patients than in those from MDS-IB patients and HD (Supplementary Fig. 9B, C, and Supplementary Table 5). Here, PLK1 is linked to Huntington disease.