Gene Set Enrichment Analysis (GSEA) revealed that gene sets related to cell cycle progression, especially mitosis (gene sets highlighted in red) including “AURKA_ACTIVATION_BY_TPX2,” “REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION,” and “POLO_LIKE_KINASE_MEDIATED_EVENTS,” were positively enriched whereas inflammatory response genes were negatively enriched, in BM CD34+ cells from MDS patients with low platelet counts (<15 × 104/μL, n = 10) vs. those from healthy donors (HD, n = 5) (Fig. 4D, Supplementary Tables 1, 2). The gene discussed is CD34; the disease is myelodysplastic syndrome.