In univariable analysis (Table 2), ischemic stroke patients could be identified by age (53% sensitivity and 64% specificity); diastolic blood pressure (DBP, 71% sensitivity and 47% specificity); and the concentrations of EVs derived from activated platelets (CD62p+, 54% sensitivity and 66% specificity) and leukocytes (CD45+, 55% sensitivity and 67% specificity). This evidence concerns the gene SELP and ischemic stroke.