Although the MFN1 editing site is located within a previously defined APOBEC3A consensus motif (5’-UCG-3’) flanked by palindromic sequences10 (Fig. 4A), MFN1 editing frequencies in the CLL cohorts and normal B cells did not positively correlate with any APOBEC expression levels (Fig. 4B). Here, MFN1 is linked to B-cell chronic lymphocytic leukemia.