In particular, these features include the release of damage-associated molecular patterns (DAMPs) after inducing tumor cell death that leads to dendritic cell activation to facilitate antigen uptake and migration to lymph nodes, ADC-mediated reduction of regulatory T cells (Tregs), augmentation of major histocompatibility complex (MHC) class I expression to promote activity of cytotoxic T cells, and enhancement of leukocyte infiltration, expansion, and interferon gamma (IFNγ) production55. This evidence concerns the gene IFNG and neoplasm.