RNASET2 and Cowden disease: For example, we identified LTR2B_dup15-chr6 as a regulator of RNASET2 in CD4-T cells (Fig. 6c), and SMR analysis showed that both LTR2B_dup15-chr6 (Fig. 5e) and RNASET2 (Fig. 6d) are genetically associated with CD.