CD8A and neoplasm: In terms of the tumor CD8+ T-cell phenotypes, effector memory CD8+ T cells were the predominant CD8+ T cells (>50%) in the controls and 3 treatment groups and changed very little in the 2-d window analyzed, including a small but significant increase of the central memory subset with IGRT alone and IGRT/TAT/immunocytokine therapy (Fig. 6F).