Cancer cells expressed multiple SASP-associated CC (e.g., CCL20) and CXC (e.g., CXCL1, CXCL8, CXCL16) chemokines, which have been shown to be induced by radiotherapy in preclinical models (20, 21, 36–38) (Figure 1B). This evidence concerns the gene CXCL8 and cancer.