NLRP3 and cardiac arrest: revealed that EA mitigates brain injury after asphyxial cardiac arrest through α7nAChR‐dependent suppression of microglial NLRP3 inflammasome activation.[37] Our prior study established EA's efficacy in alleviating periodontitis through immune homeostasis and modulating periodontal microbiota composition.[20] Extending these findings, the current study confirms that EA exerts anti‐inflammatory effects via α7nAChR activation on periodontal macrophages — effects abolished by the α7nAChR antagonist MLA.