GATA4 and Hepatic fibrosis: Using Clec4g-iCre/Gata4fl/fl mice with liver endothelial-specific loss of Gata4 late in fetal life, we demonstrated that endothelial GATA4 controls metabolic dysfunction-associated steatohepatitis (MASH)-like perisinusoidal liver fibrosis by preventing a pathogenic switch in angiocrine signaling.10