SIRT1 and cancer: HuR, widely recognized as a survival-promoting factor in various cancers, regulates the stability of transcripts encoding both pro-apoptotic proteins (e.g., p53, p27, Caspase-8, Caspase-9, FAS, c-Myc) and anti-apoptotic proteins (e.g., B-cell lymphoma 2 [BCL2], Sirtuin 1 [SIRT1], prothymosin α [PTMA]) [177–179].