While the role of myeloid HuR in MASLD has not yet been studied, hepatocyte-specific HuR-deficient mice fed a WD diet for four weeks exhibited increased liver inflammation, characterized by F4/80-positive macrophage infiltration and upregulation of Ccl2, Tnf, Il6, and Il1b [102]. Here, IL1B is linked to metabolic dysfunction-associated steatotic liver disease.