For instance, following 4 weeks of HFD feeding, increased hepatic steatosis in liver-specific HuR-deficient mice was associated with significantly reduced ATP levels and the downregulation of electron transport chain proteins, including cytochrome c (Cytc), NADH: ubiquinone oxidoreductase subunit B6 (Ndufb6), and ubiquinol–cytochrome c reductase binding protein (Uqcrb) [119]. The gene discussed is NDUFB6; the disease is fatty liver disease.