In the context of bladder cancer, METTL1 has been shown to promote proliferation, invasion, and migration by modifying tRNAs in an m7G-dependent manner, which enhances the translational efficiency of EGFR/EFEMP1 and TROP2 (Chen et al., 2023b; Ying et al., 2021). The gene discussed is METTL1; the disease is urinary bladder carcinoma.