While the 10 proteins shown in Figure 6B are all heavily involved in the cause or progression of Alzheimer’s disease, ApoE4 was selected as the protein target for this study as it was ranked as a top genetic risk factor by this study and other studies (Vassar, 2017; Fernandez et al., 2019; Safieh et al., 2019). Here, APOE is linked to early-onset autosomal dominant Alzheimer disease.