Despite the initial progress in the development of predictive models for WD-related hepatic conditions—such as the hepatic fibrosis prediction model for patients with lipid metabolism disorders established by Zhao et al. (11) and the serum non-ceruloplasmin-bound copper prediction model developed by Tao et al. (12)—a significant gap remains in the availability of robust, quantitative predictive tools for advanced hepatic fibrosis. This evidence concerns the gene CP and Hepatic fibrosis.