We observed that the IC50 values for both Erlotinib and TTI‐101 were higher in PNT2 cells (17.8 and 29.7 μm, respectively) than in LNCaP cells (5.4 and 13.1 μm, respectively) (Fig. 3A), suggesting that PCa cells are more sensitive to EGFR or STAT3 inhibition than nontumorigenic prostate cells. This evidence concerns the gene STAT3 and posterior cortical atrophy.