Increased risk of pneumonia was evident in the subgroup with hypertension (hazard ratio, 1.689, 95% CI, 1.193 to 2.417), diabetes mellitus (hazard ratio 1.372, 95% CI, 1.088 to 1.730), aged ≥ 65 years (hazard ratio 1.423, 95% CI, 1.094 to 1.852), and serum albumin < 3.5 g/dL (hazard ratio 1.739, 95% CI, 1.101 to 1.738). The gene discussed is ALB; the disease is pneumonia.