The pathogenic CFTR c.2052dupA (p.Gln685ThrfsTer4) (Q685Tfs*4, or 2184insA) variant (most likely originating from the former Galicia community) is present in the ClinVar database (Variation ID: 35838) [39] and has been reported in the literature in several individuals affected by FC with exocrine pancreatic insufficiency (EPI) [40,50,51,52,53,54,55,56,57]. This evidence concerns the gene CFTR and exocrine pancreatic insufficiency.