TLR3 and Sepsis: Alternative, rarer categories comprised congenital abnormalities in phagocyte count or function (6.15%), all identified as CGD, with a mortality rate of 8.3% (1/12) due to sepsis in an untreated infant; immune dysregulation disorders (1.54%) like ALPS and APECED, with both exhibiting 0% mortality; and deficiencies in intrinsic and innate immunity (1.54%), which included TLR-3 deficiency and chronic mucocutaneous candidiasis.