During the multiple linear regression analysis, in patients with eGFR ≥ 60 mL/min/1.73 m2, UA, but not Gal-3, was independently and positively associated with a decrease in eGFR, along with age, the existence of hypertension and the prescription of insulin, while caucasian race and male gender were inversely related to this outcome (Table 5). The gene discussed is INS; the disease is hypertensive disorder.