Beyond glioblastoma, ASIC1a’s role extends to other cancers; for instance, in breast and prostate cancers, its activation leads to reactive oxygen species (ROS) production and activation of survival pathways like AKT and NF-κB, while in pancreatic cancer, it promotes epithelial–mesenchymal transition via RhoA signalling [106]. This evidence concerns the gene AKT1 and glioblastoma.