CXCL8 and schizophrenia: On the other hand, prenatal maternal inflammation, characterized by elevated levels of C-reactive protein (CRP) and interleukin-8 (IL-8), similarly augments the child’s probability of schizophrenia, while anti-inflammatory cytokines including interleukin-4 (IL-4) and interleukin-5 (IL-5) exert protective effects.