Additional molecular evidence links prenatal influenza exposure to transcriptional dysregulation of regulator of G-protein signalling 4 (RGS4) and Mx2 [253,254], and to nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)-mediated apoptosis in dopaminergic neurones, reflecting dual dopaminergic abnormalities, striatal hyperdopaminergia and prefrontal hypodopaminergia, proposed in schizophrenia pathophysiology [255]. Here, RGS4 is linked to schizophrenia.