HLA-C and neoplasm: Across all four APC-related categories (MHC class APCs, dendritic cell (DC) APCs, tumor-associated macrophage (TAM) APCs, and Breg-like APCs), patients with high expression levels consistently exhibited poorer overall survival (MHC class APCs: p = 0.013; DC APCs: p = 0.044; TAM APCs: p = 0.0045; and Breg-like APCs: p = 0.015) (Figure 3A).