CRK and myelodysplastic syndrome: Of all the reported 17p13.3 microdeletions in MDS patients, one patient had a 2.1-Mbp deletion of the MDS locus involving the haploinsufficiency of YWHAE, CRK, OVCA1, and HIC1 but not PAFAH1B1 (Figure 1, see MDS1), and this patient displayed significant craniofacial dysmorphisms along with other MDS phenotypes [41] (Figure 2).