HNF4G and neoplasm: This action reduces HNF4G levels and limits the activation of protumorigenic genes associated with cell proliferation and EMT, thus reducing tumor invasion and metastasis However, the oncogenic role of HNF4G needs careful evaluation in clinical trials, as its overexpression may be a marker of aggressive BCa, and treatments that can selectively target overexpressed oncogenes without affecting normal cellular functions are needed [107,108,109].