RB1 and acute kidney injury: In a glycerol-induced acute renal failure (ARF) study performed on mice, it was found that in mice that received Rb1 (ARF + GS) for 48 h, creatinine (CRE) and blood urea nitrogen (BUN) were significantly reduced compared to the ARF + NS group, and showed comparable BUN and CRE to the control group (NS + NS), which did not receive glycerol-induced ARF treatment.