LRRK2 and Parkinson disease: This specificity underlies the emergence of disease-relevant signatures, for example, the enrichment of specific microRNAs like miR-9, miR-29, miR-135, and miR-186, which play a crucial role in Aβ generation [12,13] in AD, or phosphorylated Rab GTPases in PD linked to LRRK2 [13,14,15].