NLRP3 and tuberous sclerosis: A comparison of inflammasome-related hub gene expression between the two groups revealed that the expressions of IL1B, IL1A, NLRP3, TLR1, ITGAM, CCL3, and FCGR1A were significantly greater in the TSC group than in the control group, whereas no significant difference in TLR2 expression was detected between the two groups (Figure 2G).